Rectocort HC

Generic Name: hydrocortisone and pramoxine topical (HYE droe KOR ti sone and pra MOX een)

Brand Names: Analpram E, Analpram-HC, Epifoam, HC Pramoxine, Hydropram, Novacort, Pramosone, Proctofoam HC, Rectocort HC, ZyPram

What is Rectocort HC (hydrocortisone and pramoxine topical)?

Pramoxine is an anesthetic. It works by interfering with pain signals sent from the nerves to the brain.

Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.

The combination of hydrocortisone and pramoxine topical is used to treat pain, itching, or inflammation of the skin caused by a number of conditions such as allergic reactions, eczema, psoriasis, insect bites, and minor burns or scrapes. This medication is also used on the rectal area to treat itching and inflammation caused by hemorrhoids, anal fissures, or other rectal irritation.

Hydrocortisone and pramoxine topical may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Rectocort HC (hydrocortisone and pramoxine topical)?

You should not use this medication if you are allergic to hydrocortisone or pramoxine, or if you have chickenpox or measles.

Before using hydrocortisone and pramoxine topical, tell your doctor if you are allergic to any drugs or any other anesthetics or "numbing medicines."

Hydrocortisone and pramoxine topical will not treat a bacterial, fungal, or viral skin infection. If you have a skin infection, you should not use this medication until your infection is treated and clears up.

Avoid using this medication on your face, near your eyes, or on body areas where you have skin folds or thin skin.

Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of topical hydrocortisone. Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with hydrocortisone topical can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days.

Do not use hydrocortisone and pramoxine topical for any condition that has not been checked by a doctor.

What should I discuss with my health care provider before using Rectocort HC (hydrocortisone and pramoxine topical)?

You should not use this medication if you are allergic to hydrocortisone or pramoxine, or if you have chickenpox or measles.

Before using hydrocortisone and pramoxine topical, tell your doctor if you are allergic to any drugs or any other anesthetics or "numbing medicines." Also tell your doctor if you have:

• 
  

  liver disease;

  
  


• 
  

  diabetes;

  
  


• 
  

  problems with your eyes;

  
  


• 
  

  a stomach or intestinal disorder;

  
  


• 
  

  a rectal sore or infection; or

  
  


• 
  

  if you use any drugs that weaken the immune system, including steroids.

  
  

Hydrocortisone and pramoxine topical will not treat a bacterial, fungal, or viral skin infection. If you have a skin infection, you should not use this medication until your infection is treated and clears up.

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before using hydrocortisone and pramoxine topical, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether hydrocortisone and pramoxine topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of topical hydrocortisone.

How should I use Rectocort HC (hydrocortisone and pramoxine topical)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Hydrocortisone and pramoxine topical is usually applied 3 or more times daily, depending on which form of this medication you use. Follow the label directions or your doctor's instructions about how much of this medication to use and how often. Do not use hydrocortisone and pramoxine topical for any condition that has not been checked by a doctor.

Wash your hands before and after applying this medication, unless you are using hydrocortisone and pramoxine topical to treat a hand condition.

When using this medication on the skin, apply just enough of the medication to cover the area to be treated. Rub in gently.

Avoid using this medication on your face, near your eyes or mouth, or on body areas where you have skin folds or thin skin.

Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with hydrocortisone topical can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.

Before apply the rectal form of this medication (cream, lotion, or foam), clean the rectal area with mild soap and pat dry.

Use only a small amount of medicine when applying hydrocortisone and pramoxine around the outside of the rectum. You may first place the medicine onto a clean tissue and then wipe it gently onto your rectum.

When using this medication inside the rectum, insert only the applicator tip of the medicine tube or foam can into the anus, no deeper than 1 inch.

Shake the hydrocortisone and pramoxine rectal foam before each use. Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days, or if your condition clears up and then comes back. Do not stop using hydrocortisone and pramoxine topical suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when you stop using the medication. Store this medication at room temperature away from moisture and heat. Keep the rectal foam canister away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty canister.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of hydrocortisone and pramoxine topical is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using Rectocort HC (hydrocortisone and pramoxine topical)?

Avoid using this medication on your face, near your eyes, or on body areas where you have skin folds or thin skin. If it does get into any of these areas, wash with water. Do not use hydrocortisone and pramoxine topical on deep skin wounds, blistered skin, severe burns, irritated skin, or large skin areas. Also avoid using this medication in open wounds.

Avoid applying other skin medications on the same treatment area with hydrocortisone and pramoxine topical, unless your doctor has told you to.

Using a steroid can lower the blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medicines.

Hydrocortisone pramoxine topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  blurred vision, or seeing halos around lights;

  
  


• 
  

  uneven heartbeats;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  ongoing headache;

  
  


• 
  

  weight gain, puffiness in your face;

  
  


• 
  

  increased thirst or urination, weight loss, unusual weakness;

  
  


• 
  

  fever, sore throat, tired feeling;

  
  


• 
  

  severe pain, burning, or irritation of treated skin;

  
  


• 
  

  rectal bleeding;

  
  


• 
  

  any new redness or swelling where the medicine was applied; or

  
  


• 
  

  itching, oozing, or other signs of infection.

  
  

Less serious side effects may include:

• 
  

  mild skin redness, burning, itching, dryness, or peeling;

  
  


• 
  

  acne;

  
  


• 
  

  changes in the color of treated skin;

  
  


• 
  

  thinning of your skin;

  
  


• 
  

  blistering skin; or

  
  


• 
  

  stretch marks.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rectocort HC (hydrocortisone and pramoxine topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied hydrocortisone and pramoxine. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Rectocort HC resources

• Rectocort HC Side Effects (in more detail)
• Rectocort HC Use in Pregnancy & Breastfeeding
• Rectocort HC Drug Interactions
• Rectocort HC Support Group
• 0 Reviews for Rectocort HC - Add your own review/rating

• Analpram-HC Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Epifoam Prescribing Information (FDA)


• Epifoam Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Novacort MedFacts Consumer Leaflet (Wolters Kluwer)


• Pramosone Prescribing Information (FDA)


• Pramosone Lotion MedFacts Consumer Leaflet (Wolters Kluwer)


• Proctocream HC Prescribing Information (FDA)


• Proctofoam HC Prescribing Information (FDA)


• Proctofoam HC Foam MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Rectocort HC with other medications

• Dermatitis
• Dermatological Disorders
• Hemorrhoids
• Psoriasis

Where can I get more information?

• Your pharmacist can provide more information about hydrocortisone and pramoxine topical.

See also: Rectocort HC side effects (in more detail)

Regitine

Generic Name: phentolamine (Injection route)

fen-TOL-a-meen

Commonly used brand name(s)

In the U.S.

• OraVerse


• Regitine

Available Dosage Forms:

• Solution


• Injectable


• Powder for Solution

Therapeutic Class: Antihypertensive

Pharmacologic Class: Alpha-Adrenergic Blocker

Uses For Regitine

Phentolamine given by injection causes blood vessels to expand, thereby increasing blood flow. When injected into the penis (intracavernosal), it increases blood flow to the penis, which results in an erection.

This medicine should not be used as a sexual aid by men who do not have erectile dysfunction. If the medicine is not used properly, permanent damage to the penis and loss of the ability to have erections could result.

Phentolamine may also be used to reverse the effects of an anesthetic medicine in soft tissues, such as the lips and tongue. It may be used to help quickly restore normal sensation and function in patients who have received local dental anesthesia .

Phentolamine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, phentolamine is used in certain patients with the following medical conditions:

• Low doses of a three-drug combination of phentolamine, papaverine, and alprostadil as an injection may be used to treat erectile dysfunction.

Before Using Regitine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of phentolamine for the reversal of soft-tissue anesthesia in children younger than 6 years of age. Safety and efficacy have not been established .

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Although there is no specific information comparing the use of phentolamine for erectile dysfunction in the elderly, it is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Tadalafil

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acebutolol


• Alprenolol


• Atenolol


• Betaxolol


• Bevantolol


• Bisoprolol


• Bucindolol


• Carteolol


• Carvedilol


• Celiprolol


• Dilevalol


• Esmolol


• Labetalol


• Levobunolol


• Mepindolol


• Metipranolol


• Metoprolol


• Nadolol


• Nebivolol


• Oxprenolol


• Penbutolol


• Pindolol


• Propranolol


• Sotalol


• Talinolol


• Tertatolol


• Timolol


• Vardenafil

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems—These conditions increase the risk of bleeding at the place of injection.

• Priapism (history of) or


• Sickle cell disease—Patients with these conditions have an increased risk of priapism (erection lasting longer than 4 hours) while using phentolamine.

Proper Use of phentolamine

This section provides information on the proper use of a number of products that contain phentolamine. It may not be specific to Regitine. Please read with care.

To give the injection:

• Cleanse the injection site with alcohol. Using a sterile needle, inject the medicine slowly and directly into the base of the penis as instructed by your doctor. It should not be injected just under the skin. The injection is usually not painful, although you may feel some tingling in the tip of your penis. If the injection is very painful or you notice bruising or swelling at the place of injection, that means you are injecting the medicine under the skin. Stop, withdraw the needle, and reposition it properly before continuing with the injection.


• After you have completed the injection, put pressure on the place of injection to prevent bruising. Then massage your penis as instructed by your doctor. This helps the medicine spread to all parts of the penis, so that it will work better.

This medicine usually begins to work in about 10 minutes. You should attempt intercourse within 2 hours after injecting the medicine.

To reverse the effects of a soft-tissue anesthetic medicine, a dentist or other trained health professional will give you this medicine. This medicine is usually injected at the same spot where you have received the local dental anesthesia .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection dosage form:
  
  • For the treatment of impotence:
    
    • Adults— 0.5 to 1 milligram (mg) injected very slowly into the area of your penis as directed by your doctor. Allow one or two minutes to completely inject the dose. Do not inject more than one dose in a day. Also, do not use this medicine more than two days in a row or more than three times a week.
    
    
  
  

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Regitine

Use the injection exactly as directed by your doctor. Do not use more of it and do not use it more often than ordered. If too much is used, the erection may become so strong that it lasts too long and does not reverse when it should. This condition is called priapism, and it can be very dangerous. If the effect is not reversed, the blood supply to the penis may be cut off and permanent damage may occur.

Contact your doctor immediately if the erection lasts for longer than 4 hours or if it becomes painful. This may be a sign of priapism and must be treated right away to prevent permanent damage.

If you notice bleeding at the site when you inject the medicine, put pressure on the spot until the bleeding stops. If it doesn't stop, check with your doctor.

It is important for you to examine your penis regularly. Check with your doctor if you find a lump where the medicine has been injected or if you notice that your penis is becoming curved. These may be signs that unwanted tissue is growing (called fibrosis), which should be seen by your doctor.

Regitine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Dizziness


• erection continuing for more than 4 hours, or painful erection


• lumps in the penis

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

• Bruising or bleeding at place of injection


• burning (mild) along penis


• difficulty in ejaculating


• swelling at place of injection

Phentolamine injected into the penis may cause tingling at the tip of the penis. This is no cause for concern.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Regitine side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Regitine resources

• Regitine Side Effects (in more detail)
• Regitine Use in Pregnancy & Breastfeeding
• Regitine Drug Interactions
• Regitine Support Group
• 0 Reviews for Regitine - Add your own review/rating

• Regitine Prescribing Information (FDA)


• Phentolamine Prescribing Information (FDA)


• Phentolamine Professional Patient Advice (Wolters Kluwer)


• OraVerse Prescribing Information (FDA)


• OraVerse Consumer Overview


• Phentolamine Mesylate Monograph (AHFS DI)

Compare Regitine with other medications

• Dermal Necrosis, Treatment
• Pheochromocytoma
• Pheochromocytoma Diagnosis

Raloxifene

Pronunciation: ral-OX-i-feen
Generic Name: Raloxifene
Brand Name: Evista

Raloxifene may increase the risk of serious blood clots. Do not take Raloxifene if you have a history of serious blood clots (eg, in the lung, leg, or eye).

Raloxifene may increase the risk of death from stroke in patients who have coronary heart disease or who are at risk for certain serious heart problems. If you have heart problems or are at risk for a serious heart problem, talk with your doctor to be sure that the benefits of using Raloxifene outweigh the risks.

Raloxifene is used for:

Treating and preventing osteoporosis (bone thinning) in women who are past menopause. It is also used to reduce the risk of invasive breast cancer in certain women who are past menopause. It may also be used for other conditions as determined by your doctor.

Raloxifene is a selective estrogen receptor modulator (SERM). It works in osteoporosis by decreasing bone breakdown and thinning that may occur in women after menopause. It works to decrease the risk of invasive breast cancer by blocking estrogen in breast and uterine tissue.

Do NOT use Raloxifene if:

• you are allergic to any ingredient in Raloxifene


• you are pregnant, could become pregnant, or are breast-feeding


• you have not yet gone through menopause


• you have a history of blood clots in your legs, lungs, or eyes


• you are taking an anion exchange resin (eg, cholestyramine, colestipol) or estrogen

Contact your doctor or health care provider right away if any of these apply to you.

Before using Raloxifene:

Some medical conditions may interact with Raloxifene. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of liver problems, kidney problems, breast cancer, or any other type of cancer


• if you have a history of stroke, transient ischemic attack (TIA), blood vessel problems, heart problems, (eg, heart failure, irregular heartbeat), or high blood pressure


• if you are at risk for stroke or heart problems


• if you will be having surgery, you smoke or drink alcohol, you are not able to absorb nutrients properly (gastrointestinal malabsorption syndrome), or you have very poor health


• if you are taking an estrogen or have a history of high triglyceride levels while taking an estrogen


• if anyone in your family has a history of serious blood clots

Some MEDICINES MAY INTERACT with Raloxifene. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anion exchange resins (eg, cholestyramine) because they may decrease Raloxifene's effectiveness


• Diazepam, diazoxide, or lidocaine because the risk of their side effects may be increased by Raloxifene.


• Anticoagulants (eg, warfarin) because their effectiveness may be decreased by Raloxifene

This may not be a complete list of all interactions that may occur. Ask your health care provider if Raloxifene may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Raloxifene:

Use Raloxifene as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Raloxifene comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Raloxifene refilled.


• Take Raloxifene by mouth with or without food.


• Take Raloxifene on a regular schedule to get the most benefit from it. Taking Raloxifene at the same time each day will help you remember to take it.


• Continue to take Raloxifene even if you feel well. Do not miss any doses.


• If you miss a dose of Raloxifene, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Raloxifene.

Important safety information:

• Follow the diet and exercise program given to you by your health care provider. Talk with your doctor about whether you should take a calcium and vitamin D supplement while you use Raloxifene.


• Talk with your doctor about the use of weight-bearing exercises to help prevent weak bones.


• Raloxifene should be stopped at least 72 hours before surgery or any time you will be confined to a bed or chair for a long period of time (eg, long car ride, long plane flight, bedrest, illness). Tell your doctor or dentist that you take Raloxifene before you receive any medical or dental care, emergency care, or surgery. Tell your doctor if you will be traveling, or any other time you may be confined to a bed or chair.


• If you are traveling (eg, long car ride or plane ride), try to avoid sitting in one place for a long time. Be sure to get up and move around as often as possible to help avoid the risk of blood clots.


• Raloxifene is not recommended for use in men.


• Lab tests and medical exams, including bone density, breast exams, and mammograms, may be performed while you use Raloxifene. They may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Raloxifene should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not use Raloxifene if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Raloxifene is found in breast milk. Do not breast-feed while taking Raloxifene.

Possible side effects of Raloxifene:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Hot flashes; increased sweating; joint aches; leg cramps.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal vaginal bleeding; back or side pain; blurred vision, loss of vision, or other vision changes; breast pain, tenderness, swelling, lump or discharge; chest pain; coughing up blood; confusion; flu-like symptoms; leg or calf pain, warmth, or swelling; one-sided weakness; shortness of breath; slurred speech; swelling of the hands, arms, legs or feet; unexplained bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Raloxifene side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; dizziness; flushing; loss of coordination; severe leg cramps; tremor; vomiting.

Proper storage of Raloxifene:

Store Raloxifene at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Raloxifene out of the reach of children and away from pets.

General information:

• If you have any questions about Raloxifene, please talk with your doctor, pharmacist, or other health care provider.


• Raloxifene is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Raloxifene. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Raloxifene resources

• Raloxifene Side Effects (in more detail)
• Raloxifene Use in Pregnancy & Breastfeeding
• Raloxifene Drug Interactions
• Raloxifene Support Group
• 2 Reviews for Raloxifene - Add your own review/rating

• raloxifene Advanced Consumer (Micromedex) - Includes Dosage Information


• Evista Prescribing Information (FDA)


• Evista Monograph (AHFS DI)


• Evista Consumer Overview

Compare Raloxifene with other medications

• Breast Cancer, Prevention
• Osteoporosis
• Prevention of Osteoporosis

Radiogardase

Generic Name: prussian blue (Oral route)

PRUSH-un bloo

Commonly used brand name(s)

In the U.S.

• Radiogardase

Available Dosage Forms:

• Capsule

Therapeutic Class: Pigmentation Agent

Uses For Radiogardase

Prussian blue is used to treat thallium poisoning and radiocesium poisoning. It works by combining with thallium and radiocesium in the intestines. The combination is then removed from the body through the stools. By removing the thallium or radiocesium, the medicine lessens damage to your body's organs and tissues.

Prussian blue is available only with your doctor's prescription.

Before Using Radiogardase

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of prussian blue in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of prussian blue in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Blockage of the intestines or


• Constipation—This medicine may not work properly if these conditions are present

Proper Use of Radiogardase

Keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.

If you are unable to swallow the capsule, you may open the capsule and empty the contents into a glass (8 ounces) of warm water. Stir gently until the medicine is mixed with the water. Drink the water with the medicine right away. If there is any medicine left in the bottom of the glass, add a little more warm water to the glass and drink that too.

Your doctor may advise you to take this medicine with a laxative, such as sorbitol, to help prevent constipation.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (capsules):
  
  • For acute thallium poisoning:
    
    • Adults and children—3 grams taken right away, followed by 3 to 20 grams a day divided into smaller doses as directed by your doctor. Or, the dose may be 3 grams taken right away, followed by 250 milligrams (mg) per kilogram (kg) (113.5 mg per pound) of body weight a day divided into four smaller doses. Either dose may be taken for two to three weeks as determined by your doctor.
    
    
  
  
  • For chronic thallium poisoning:
    
    • Adults and children—The usual dose is 3 to 20 grams a day divided into smaller doses as directed by your doctor. Or, the dose may be 250 mg per kg (113.5 mg per pound) of body weight a day divided into four smaller doses. Either dose may be taken for two to three weeks as determined by your doctor.
    
    
  
  
  • For radiocesium poisoning:
    
    • Adults and children—The usual dose is 500 mg every two hours, for a total dose of 3000 mg (3 grams) a day. This dose may be taken for as little as several days or as long as three weeks, as determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Radiogardase Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Constipation

This medicine commonly causes unusually dark stools. This side effect does not usually need medical attention.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Radiogardase resources

• Radiogardase Support Group
• 0 Reviews for Radiogardase - Add your own review/rating

• Radiogardase Monograph (AHFS DI)


• Radiogardase Concise Consumer Information (Cerner Multum)


• Prussian Blue Professional Patient Advice (Wolters Kluwer)

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• Radiation Emergency

Rabies Vaccine

Pronunciation: RAY-beez
Generic Name: Rabies Vaccine
Brand Name: RabAvert

Rabies Vaccine is used for:

Preventing rabies before and after exposure.

Rabies Vaccine is a vaccine. It works by stimulating the immune system to produce antibodies against the rabies virus.

Do NOT use Rabies Vaccine if:

• you are allergic to any ingredient in Rabies Vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Rabies Vaccine:

Some medical conditions may interact with Rabies Vaccine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have an infection or are allergic to eggs

Some MEDICINES MAY INTERACT with Rabies Vaccine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Aminoquinolines (eg, chloroquine), antimalarials (eg, atovaquone), corticosteroids (eg, hydrocortisone), or radiation therapy because the effectiveness of Rabies Vaccine may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Rabies Vaccine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Rabies Vaccine:

Use Rabies Vaccine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Rabies Vaccine is usually administered as injection at your doctor's office, hospital, or clinic. If you are using Rabies Vaccine at home, carefully follow the injection procedures taught to you by your health care provider.


• It will take 7 to 10 days for Rabies Vaccine to work. When all doses have been received, Rabies Vaccine should protect against rabies for 2 or more years.


• If Rabies Vaccine contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.


• Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.


• If you miss a dose of Rabies Vaccine, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Rabies Vaccine.

Important safety information:

• Rabies Vaccine may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Rabies Vaccine.


• You may need more than 1 injection for full protection.


• Make sure your doctor knows your current health status and if you have had an allergic reaction to a rabies vaccine in the past.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Rabies Vaccine during pregnancy. If you are or will be breast-feeding while you are using Rabies Vaccine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Rabies Vaccine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Chills; dizziness; general body discomfort; headache; itching; mild fever; stomach pain; tiredness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty swallowing; hoarseness; joint or muscle pain; numbness or tingling; pain, redness, or swelling at the injection site; paralysis.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Rabies side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Rabies Vaccine:

Rabies Vaccine is usually handled and stored by a health care provider. If you are using Rabies Vaccine at home, store Rabies Vaccine as directed by your pharmacist or health care provider.

General information:

• If you have any questions about Rabies Vaccine, please talk with your doctor, pharmacist, or other health care provider.


• Rabies Vaccine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Rabies Vaccine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Rabies Vaccine resources

• Rabies Vaccine Side Effects (in more detail)
• Rabies Vaccine Use in Pregnancy & Breastfeeding
• Rabies Vaccine Drug Interactions
• Rabies Vaccine Support Group
• 0 Reviews for Rabies - Add your own review/rating

Compare Rabies Vaccine with other medications

• Rabies Prophylaxis

RespiVent Dosepack DF

chlorpheniramine maleate, methscopolamine nitrate

Dosage Form: tablets
RespiVent Dosepack DF

RespiVent Dosepack DF Description

Each AM tablet contains:                               

Chlorpheniramine Maleate. ….4 mg                

Methscopolamine Nitrate…..2.5 mg                               

Each PM tablet contains:

Chlorpheniramine Maleate. ….8 mg                                 

Methscopolamine Nitrate…..2.5 mg

Chlorpheniramine maleate is an antihistamine having the chemical name 2-pyridinepropanamine, gamma-(4 chlorophenyl)-N, N-dimethyl-, (Z)-2-butenedioate (1:1).

Chlorpheniramine maleate

Methscopolamine nitrate is an anticholinergic having the chemical name 3-oxa-9-azoniatricyclo [3.3.1.0 2 4] nonane, 7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9, 9-dimethyl-,nitrate, [7(S)-(1α, 2β, 4β, 5α, 7β)]; C17H21NO4•CH3NO3, MW = 80.4

Methscopolamine nitrate

Inactive Ingredients:

AM tablets: Each white AM tablet contains Hypromellose, Dicalcium Phosphate, Talc, Stearic Acid and Magnesium Stearate.

PM tablets: Each blue PM tablet contains Hypromellose, Dicalcium Phosphate, Talc, FD&C Blue #1 (aluminum lake) Dye, Stearic Acid and Magnesium Stearate.

CLINICAL PHARMACOLOGY

Chlorpheniramine maleate is an alkylamine-type antihistamine. This group of antihistamines is among the most active histamine antagonists and is generally effective in relatively low doses.

Methscopolamine nitrate is a quaternary ammonium derivative of the anticholinergic scopolamine which possesses the peripheral actions of the belladonna alkaloids, but does not exhibit the central actions because of its lack of ability to cross the blood-brain

barrier. Its antimuscarinic effect causes inhibition of salivary secretions, reduction in volume and total acid content of gastric secretion, and inhibition of gastrointestinal motility. It is poorly and unreliably absorbed. Drug effects appear in about one hour and

persist for about 4 to 6 hours. It is excreted primarily in the urine and bile, or as unabsorbed drug in feces.

INDICATIONS AND USAGE

For the temporary relief of symptoms associated with allergic rhinitis.

CONTRAINDICATIONS

This product is contraindicated in patients with hypersensitivity to methscopolamine nitrate and chlorpheniramine maleate. RespiVent™ DF is contraindicated in patients with severe hypertension, severe coronary artery disease, and in nursing mothers.

RespiVent™ DF is also contraindicated in patients with narrow-angle glaucoma, and peptic ulcer.

WARNINGS

Antihistamines may cause excitability, especially in children. At dosages higher than the recommended dose, nervousness, dizziness, or sleeplessness may occur. Do not exceed recommended dosage. Methscopolamine nitrate may produce drowsiness or blurred vision. The patient should be cautioned regarding activities requiring mental alertness such as operating a motor vehicle or performing hazardous work while taking RespiVent™ DF.

Co-administration of sildenafil citrate and other organic nitrates has been shown to potentiate the hypotension effects of nitrates. Co-administration of RespiVent™ DF and sildenafil citrate has not been studied. Therefore, the use of sildenafil citrate and RespiVent™ DF together is not recommended.

Precautions

General

RespiVent™ DF should be used with caution in patients with diabetes mellitus, hypertension, and cardiovascular disease.  Antihistamines may cause drowsiness, and ambulatory patients who operate machinery or motor vehicles should be cautioned accordingly. Methscopolamine nitrate should be used with caution in the elderly and all patients with autonomic neuropathy, hepatic or renal disease, or ulcerative colitis.

Drug Interactions

Additive anticholinergic effects may result from concomitant use with antipsychotics, tricyclic antidepressants, and other drugs with anticholinergic effects. Concomitant administration with antacids may interfere with the absorption of methscopolamine nitrate.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Animal studies to assess the long-term carcinogenic and mutagenic potential or the effect on fertility in animals or humans have not been performed.

Pregnancy Category C

It is not known whether RespiVent™ DF can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.  RespiVent™ DF should be given to a pregnant woman only if clearly needed.

Nursing Mothers

It is not known whether this combination drug is excreted in human milk.

Pediatric Use

The safety and effectiveness in children under 12 years of age have not been established.

Geriatric Use

The elderly (60 years and older) are more likely to experience adverse reactions to methscopolamine.

ADVERSE REACTIONS

Adverse reactions include drowsiness, lassitude, nausea, giddiness, dryness of mouth, blurred vision, and increased irritability or excitement (especially in children). Antihistamines and anticholinergics may cause drowsiness, dizziness, blurred vision, and excessive dryness of the nose, throat, and mouth.

OVERDOSAGE AND TREATMENT OF OVERDOSAGE

The treatment of overdosage should provide symptomatic and supportive care.  Induction of emesis and gastric lavage may be performed if the patient is alert and seen within early hours after ingestion. Drug remaining in the stomach may be absorbed by the administration of activated charcoal. Since the effects of RespiVent™ DF last up to 12 hours, the patient should be monitored for at least that length of time and treated as necessary.

DOSAGE AND ADMINISTRATION

Adults and adolescents 12 years of age and over: One white AM tablet in the morning and one blue PM tablet in the evening.  RespiVent™ DF is not recommended for children under 12 years of age.

HOW SUPPLIED

(NDC 24486-704-20) RespiVent™ DF Tablets 10 Day Treatment Regimen, containing 20 tablets as follows:

10 white elongated and scored AM tablets debossed with “CBP” on one side and "03" to the right of the score on the other side, each containing 4 mg of chlorpheniramine maleate and 2.5 mg of methscopolamine nitrate.

10 blue, elongated and scored PM tablets debossed with “CBP” on one side and "02" to the right of the score on the other side, each containing 8 mg of chlorpheniramine maleate and 2.5 mg of methscopolamine nitrate.

(NDC 24486-704-60) RespiVent™ DF Tablets 30 Day Treatment Regimen, containing 60 tablets as follows:

30 white elongated and scored AM tablets debossed with “CBP” on one side and "03" to the right of the score on the other side, each containing 4 mg of chlorpheniramine maleate and 2.5 mg of methscopolamine nitrate.

30 blue, elongated and scored PM tablets debossed with “CBP” on one side and "02" to the right of the score on the other side, each containing 8 mg of chlorpheniramine maleate and 2.5 mg of methscopolamine nitrate.

Keep out of reach of pediatric population.

Store at 20° - 25°C (68° - 77°F); excursions permitted to 15° - 30°C (59° - 86°F). See USP Controlled Room Temperature.

Distributed by Aristos Pharmaceuticals, LLC., Cary, NC 27518.

Patent Pending

Aristos Pharmaceuticals

ARR202A0108

RespiVent Dose Pack DF

RespiVent Dosepack DF  chlorpheniramine maleate methscopolamine nitrate  kit

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 24486-704

Packaging # NDC Package Description Multilevel Packaging 1 24486-704-20 1 KIT In 1 BLISTER PACK None

QUANTITY OF PARTS Part # Package Quantity Total Product Quantity Part 1 1 BLISTER PACK   10  Part 2 1 BLISTER PACK   10

Part 1 of 2 CHLORPHENIRAMINE MALEATE METHSCOPOLAMINE NITRATE  chlorpheniramine maleate methscopolamine nitrate  tablet

Product Information       Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength CHLORPHENIRAMINE MALEATE (CHLORPHENIRAMINE) CHLORPHENIRAMINE MALEATE 4 mg METHSCOPOLAMINE NITRATE (METHSCOPOLAMINE) METHSCOPOLAMINE NITRATE 2.5 mg

Inactive Ingredients Ingredient Name Strength HYPROMELLOSE   ANHYDROUS DIBASIC CALCIUM PHOSPHATE   TALC   STEARIC ACID   MAGNESIUM STEARATE

Product Characteristics Color WHITE (white) Score 2 pieces Shape OVAL Size 11mm Flavor Imprint Code CBP;03 Contains

Packaging # NDC Package Description Multilevel Packaging 1 10 TABLET In 1 BLISTER PACK None

Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date UNAPPROVED DRUG OTHER 07/01/2008

Part 2 of 2 CHLORPHENIRAMINE MALEATE METHSCOPOLAMINE NITRATE  chlorpheniramine maleate methscopolamine nitrate  tablet

Product Information       Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength CHLORPHENIRAMINE MALEATE (CHLORPHENIRAMINE) CHLORPHENIRAMINE MALEATE 8 mg METHSCOPOLAMINE NITRATE (METHSCOPOLAMINE) METHSCOPOLAMINE NITRATE 2.5 mg

Inactive Ingredients Ingredient Name Strength HYPROMELLOSE   ANHYDROUS DIBASIC CALCIUM PHOSPHATE   TALC   FD&C BLUE NO. 1   STEARIC ACID   MAGNESIUM STEARATE

Product Characteristics Color BLUE Score 2 pieces Shape OVAL Size 11mm Flavor Imprint Code CBP;02 Contains

Packaging # NDC Package Description Multilevel Packaging 1 10 TABLET In 1 BLISTER PACK None

Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date UNAPPROVED DRUG OTHER 07/01/2008

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
UNAPPROVED DRUG OTHER		07/01/2008

Labeler - Aristos Phamaceuticals Incorporated (153886994)

Revised: 10/2009Aristos Phamaceuticals Incorporated

More RespiVent Dosepack DF resources

• RespiVent Dosepack DF Side Effects (in more detail)
• RespiVent Dosepack DF Use in Pregnancy & Breastfeeding
• RespiVent Dosepack DF Drug Interactions
• RespiVent Dosepack DF Support Group
• 0 Reviews for RespiVent Dosepack DF - Add your own review/rating

Compare RespiVent Dosepack DF with other medications

• Rhinitis

RectaGel HC Cream

Pronunciation: LYE-doe-kane /hye-droe-KOR-ti-sone
Generic Name: Lidocaine/Hydrocortisone
Brand Name: Examples include AnaMantle HC and RectaGel HC

RectaGel HC Cream is used for:

Treating pain, itching, soreness, and discomfort due to hemorrhoids.

RectaGel HC Cream is an anti-inflammatory and topical anesthetic combination. It works by preventing nerves from transmitting painful impulses to the brain and decreasing inflammation around the affected area.

Do NOT use RectaGel HC Cream if:

• you are allergic to any ingredient in RectaGel HC Cream or to similar medications (eg, amide-type local anesthetics)


• you have a tuberculous or fungal infection of the skin, a herpes simplex skin infection, or a skin infection following smallpox vaccination

Contact your doctor or health care provider right away if any of these apply to you.

Before using RectaGel HC Cream:

Some medical conditions may interact with RectaGel HC Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any anesthetic medicine


• you have measles, chickenpox, a skin infection or other skin problems, or any recent vaccinations, or if you have ever had a positive tuberculin skin test


• you have heart, liver, or kidney problems

Some MEDICINES MAY INTERACT with RectaGel HC Cream. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturates (eg, phenobarbital), carbamazepine, or fluconazole because they may increase RectaGel HC Cream's effectiveness


• Amiodarone, aprepitant, beta-blockers (eg, atenolol), cimetidine, clarithromycin, estrogens (eg, ethinyl estradiol), mexiletine, oral contraceptives (eg, ethinyl estradiol/norethindrone), or rifampin because side effects, such as sluggishness, confusion, slow breathing, low blood pressure, and slow heartbeat, may occur


• Live vaccines or ritodrine because the actions and side effects of these medicines may be increased


• Hydantoins (eg, phenytoin) or mifepristone because their effectiveness may be decreased by RectaGel HC Cream

This may not be a complete list of all interactions that may occur. Ask your health care provider if RectaGel HC Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use RectaGel HC Cream:

Use RectaGel HC Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Use RectaGel HC Cream according to the directions on the package label or as directed by your doctor.


• If you miss a dose of RectaGel HC Cream and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use RectaGel HC Cream.

Important safety information:

• If you use topical products too often, your condition may become worse.


• RectaGel HC Cream has a corticosteroid in it. Before you start any new medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Tell your doctor or dentist that you take RectaGel HC Cream before you receive any medical or dental care, emergency care, or surgery.


• RectaGel HC Cream may cause a numbing effect at the application site. Do not scratch, rub, or expose the area to extreme hot or cold temperature until the numbness is gone.


• Do NOT take more than the recommended dose, apply more often, or use for longer than prescribed without checking with your doctor.


• Caution is advised when using RectaGel HC Cream in CHILDREN; they may be more sensitive to its effects. Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use RectaGel HC Cream.


• PREGNANCY and BREAST-FEEDING: It is not known if RectaGel HC Cream can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using RectaGel HC Cream while you are pregnant. It is not known if RectaGel HC Cream is found in breast milk after topical use. If you are or will be breast-feeding while you use RectaGel HC Cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of RectaGel HC Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness or swelling at the application site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); persistent irritation or infection.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: RectaGel HC side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. RectaGel HC Cream may be harmful if swallowed.

Proper storage of RectaGel HC Cream:

Store RectaGel HC Cream at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat and light. Do not store in the bathroom. Protect from freezing. Keep RectaGel HC Cream out of the reach of children and away from pets.

General information:

• If you have any questions about RectaGel HC Cream, please talk with your doctor, pharmacist, or other health care provider.


• RectaGel HC Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about RectaGel HC Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More RectaGel HC resources

• RectaGel HC Side Effects (in more detail)
• RectaGel HC Use in Pregnancy & Breastfeeding
• RectaGel HC Drug Interactions
• RectaGel HC Support Group
• 1 Review for RectaGel HC - Add your own review/rating

Compare RectaGel HC with other medications

• Hemorrhoids
• Pruritus